Single Intranasal Mucosal Mycobacterium bovis BCG Vaccination Confers Improved Protection Compared to Subcutaneous Vaccination against Pulmonary Tuberculosis
نویسندگان
چکیده
منابع مشابه
Pulmonary Mycobacterium bovis BCG vaccination confers dose-dependent superior protection compared to that of subcutaneous vaccination.
Worldwide, the Mycobacterium bovis BCG vaccine is one of the most widely used vaccines. However, it appears to be ineffective in preventing pulmonary tuberculosis. Here, we show that pulmonary BCG vaccination of mice with a broad dose range provides superior protection against Mycobacterium tuberculosis challenge compared to that of subcutaneous vaccination.
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the calmette-güerin vaccine (bcg) is administered to all the newborns in iran in order to prevent tuberculosis. complications of this vaccine are uncommon. we report disseminated bcg disease in 17 patients less than 10 years old. this is a retrospective study of total of 17 cases who were admitted in children medical center hospital with systemic syndrome compatible with mycobacterium disease w...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2004
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.72.1.238-246.2004